Critical Roles of Clostridium difficile Toxin B Enzymatic Activities in Pathogenesis

TcdB is one of the key virulence factors of Clostridium difficile that is responsible for causing serious and potentially fatal colitis. The toxin contains at least two enzymatic domains: an effector glucosyltransferase domain for inactivating host Rho GTPases and a cysteine protease domain for the...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Li, Shan, Shi, Lianfa, Yang, Zhiyong, Zhang, Yongrong, Perez-Cordon, Gregorio, Huang, Tuxiong, Ramsey, Jeremy, Oezguen, Numan, Savidge, Tor C., Feng, Hanping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294253/
https://ncbi.nlm.nih.gov/pubmed/25404023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02316-14
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