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A Chimeric Toxin Vaccine Protects against Primary and Recurrent Clostridium difficile Infection
The global emergence of Clostridium difficile infection (CDI) has contributed to the recent surge in severe antibiotic-associated diarrhea and colonic inflammation. C. difficile produces two homologous glucosylating exotoxins, TcdA and TcdB, both of which are pathogenic and require neutralization to...
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| Główni autorzy: | , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434558/ https://ncbi.nlm.nih.gov/pubmed/22615245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00215-12 |
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