Antibody-Enhanced, Fc Gamma Receptor-Mediated Endocytosis of Clostridium difficile Toxin A

Toxin A (TcdA) and toxin B (TcdB) are major virulence factors of Clostridium difficile. These two toxins intoxicate cultured cells by similar mechanisms, and TcdB generally is more potent than TcdA in cultured cells. The exact reason for this difference is unclear. Here, we report that the cellular...

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Bibliografiske detaljer
Main Authors: He, Xiangyun, Sun, Xingmin, Wang, Jufang, Wang, Xiaoning, Zhang, Quanshun, Tzipori, Saul, Feng, Hanping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687358/
https://ncbi.nlm.nih.gov/pubmed/19307220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01577-08
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