Antibody-Enhanced, Fc Gamma Receptor-Mediated Endocytosis of Clostridium difficile Toxin A

Toxin A (TcdA) and toxin B (TcdB) are major virulence factors of Clostridium difficile. These two toxins intoxicate cultured cells by similar mechanisms, and TcdB generally is more potent than TcdA in cultured cells. The exact reason for this difference is unclear. Here, we report that the cellular...

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Detalhes bibliográficos
Main Authors: He, Xiangyun, Sun, Xingmin, Wang, Jufang, Wang, Xiaoning, Zhang, Quanshun, Tzipori, Saul, Feng, Hanping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687358/
https://ncbi.nlm.nih.gov/pubmed/19307220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01577-08
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