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Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium
BACKGROUND: Major Clostridium difficile virulence factors are the exotoxins TcdA and TcdB. Due to the large size and poor stability of the proteins, the active recombinant TcdA and TcdB have been difficult to produce. RESULTS: The toxin genes tcdA and tcdB were amplified by PCR using chromosomal DNA...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586027/ https://ncbi.nlm.nih.gov/pubmed/18990232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-192 |
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