Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

BACKGROUND: Major Clostridium difficile virulence factors are the exotoxins TcdA and TcdB. Due to the large size and poor stability of the proteins, the active recombinant TcdA and TcdB have been difficult to produce. RESULTS: The toxin genes tcdA and tcdB were amplified by PCR using chromosomal DNA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yang, Guilin, Zhou, Boping, Wang, Jufang, He, Xiangyun, Sun, Xingmin, Nie, Weijia, Tzipori, Saul, Feng, Hanping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2008
Gaiak:
Methodology Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586027/
https://ncbi.nlm.nih.gov/pubmed/18990232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-192
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