Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

BACKGROUND: Major Clostridium difficile virulence factors are the exotoxins TcdA and TcdB. Due to the large size and poor stability of the proteins, the active recombinant TcdA and TcdB have been difficult to produce. RESULTS: The toxin genes tcdA and tcdB were amplified by PCR using chromosomal DNA...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Yang, Guilin, Zhou, Boping, Wang, Jufang, He, Xiangyun, Sun, Xingmin, Nie, Weijia, Tzipori, Saul, Feng, Hanping
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2008
Assuntos:
Methodology Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586027/
https://ncbi.nlm.nih.gov/pubmed/18990232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-192
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares