Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

BACKGROUND: Major Clostridium difficile virulence factors are the exotoxins TcdA and TcdB. Due to the large size and poor stability of the proteins, the active recombinant TcdA and TcdB have been difficult to produce. RESULTS: The toxin genes tcdA and tcdB were amplified by PCR using chromosomal DNA...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Guilin, Zhou, Boping, Wang, Jufang, He, Xiangyun, Sun, Xingmin, Nie, Weijia, Tzipori, Saul, Feng, Hanping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2008
Pynciau:
Methodology Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586027/
https://ncbi.nlm.nih.gov/pubmed/18990232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2180-8-192
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