Critical Roles of Clostridium difficile Toxin B Enzymatic Activities in Pathogenesis

TcdB is one of the key virulence factors of Clostridium difficile that is responsible for causing serious and potentially fatal colitis. The toxin contains at least two enzymatic domains: an effector glucosyltransferase domain for inactivating host Rho GTPases and a cysteine protease domain for the...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Li, Shan, Shi, Lianfa, Yang, Zhiyong, Zhang, Yongrong, Perez-Cordon, Gregorio, Huang, Tuxiong, Ramsey, Jeremy, Oezguen, Numan, Savidge, Tor C., Feng, Hanping
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4294253/
https://ncbi.nlm.nih.gov/pubmed/25404023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02316-14
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