Structure, dynamics and selectivity of the sodium channel blocker µ-conotoxin SIIIA,

µ-SIIIA, a novel µ-conotoxin from Conus striatus, appeared to be a selective blocker of tetrodotoxin-sensitive sodium channels in frog preparations. It also exhibited potent analgesic activity in mice, although its selectivity profile against mammalian sodium channels remained unknown. We have deter...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Yao, Shenggen, Zhang, Minmin, Yoshikami, Doju, Azam, Layla, Olivera, Baldomero M., Bulaj, Grzegorz, Norton, Raymond S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201628/
https://ncbi.nlm.nih.gov/pubmed/18798648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801010u
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares