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Structure, dynamics and selectivity of the sodium channel blocker µ-conotoxin SIIIA,
µ-SIIIA, a novel µ-conotoxin from Conus striatus, appeared to be a selective blocker of tetrodotoxin-sensitive sodium channels in frog preparations. It also exhibited potent analgesic activity in mice, although its selectivity profile against mammalian sodium channels remained unknown. We have deter...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4201628/ https://ncbi.nlm.nih.gov/pubmed/18798648 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801010u |
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