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Cooccupancy of the Outer Vestibule of Voltage-Gated Sodium Channels by μ-Conotoxin KIIIA and Saxitoxin or Tetrodotoxin
The guanidinium alkaloids tetrodotoxin (TTX) and saxitoxin (STX) are classic ligands of voltage-gated sodium channels (VGSCs). Like TTX and STX, μ-conotoxin peptides are pore blockers but with greater VGSC subtype selectivity. μ-Conotoxin KIIIA blocks the neuronal subtype Na(V)1.2 with nanomolar aff...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904204/ https://ncbi.nlm.nih.gov/pubmed/20410356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00145.2010 |
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