Structure, dynamics and selectivity of the sodium channel blocker µ-conotoxin SIIIA,

µ-SIIIA, a novel µ-conotoxin from Conus striatus, appeared to be a selective blocker of tetrodotoxin-sensitive sodium channels in frog preparations. It also exhibited potent analgesic activity in mice, although its selectivity profile against mammalian sodium channels remained unknown. We have deter...

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Hlavní autoři: Yao, Shenggen, Zhang, Minmin, Yoshikami, Doju, Azam, Layla, Olivera, Baldomero M., Bulaj, Grzegorz, Norton, Raymond S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201628/
https://ncbi.nlm.nih.gov/pubmed/18798648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801010u
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