The Mammalian Neuronal Sodium Channel Blocker μ-Conotoxin BuIIIB has a Structured N-terminus that Influences Potency

Among the μ-conotoxins that block vertebrate voltage-gated sodium channels (VGSCs), some have been shown to be potent analgesics following systemic administration in mice. We have determined the solution structure of a new representative of this family, μ-BuIIIB, and established its disulfide connec...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Kuang, Zhihe, Zhang, Min-Min, Gupta, Kallol, Gajewiak, Joanna, Gulyas, Jozsef, Balaram, Padmanabhan, Rivier, Jean E., Olivera, Baldomero M., Yoshikami, Doju, Bulaj, Grzegorz, Norton, Raymond S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201638/
https://ncbi.nlm.nih.gov/pubmed/23557677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb300674x
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars