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α- And β-subunit composition of voltage-gated sodium channels investigated with μ-conotoxins and the recently discovered μO§-conotoxin GVIIJ

We investigated the identities of the isoforms of the α (Na(V)1)- and β (Na(V)β)-subunits of voltage-gated sodium channels, including those responsible for action potentials in rodent sciatic nerves. To examine α-subunits, we used seven μ-conotoxins, which target site 1 of the channel. With the use...

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Detalles Bibliográficos
Publicado en:J Neurophysiol
Main Authors: Wilson, Michael J., Zhang, Min-Min, Gajewiak, Joanna, Azam, Layla, Rivier, Jean E., Olivera, Baldomero M., Yoshikami, Doju
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4416564/
https://ncbi.nlm.nih.gov/pubmed/25632083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.01004.2014
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