Pharmacological fractionation of tetrodotoxin-sensitive sodium currents in rat dorsal root ganglion neurons by μ-conotoxins

BACKGROUND AND PURPOSE: Adult rat dorsal root ganglion (DRG) neurons normally express transcripts for five isoforms of the α-subunit of voltage-gated sodium channels: Na(V)1.1, 1.6, 1.7, 1.8 and 1.9. Tetrodotoxin (TTX) readily blocks all but Na(V)1.8 and 1.9, and pharmacological agents that discrimi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Min-Min, Wilson, Michael J, Gajewiak, Joanna, Rivier, Jean E, Bulaj, Grzegorz, Olivera, Baldomero M, Yoshikami, Doju
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632242/
https://ncbi.nlm.nih.gov/pubmed/23351163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12119
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados