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Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells

In vivo visualization of thrombopoiesis suggests an important role for shear flow in platelet biogenesis. In vitro, shear stress was shown to accelerate proplatelet formation from mature megakaryocytes (Mks). Yet, the role of biomechanical forces on Mk biology and platelet biogenesis remains largely...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Jiang, Jinlin, Woulfe, Donna S., Papoutsakis, Eleftherios T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Hematology 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186538/
https://ncbi.nlm.nih.gov/pubmed/24948658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-547927
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