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How do megakaryocytic microparticles target and deliver cargo to alter the fate of hematopoietic stem cells?

Megakaryocytic microparticles (MkMPs), the most abundant MPs in circulation, can induce the differentiation of hematopoietic stem and progenitor cells (HSPCs) into functional megakaryocytes. This MkMP capability could be explored for applications in transfusion medicine but also for delivery of nucl...

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Dettagli Bibliografici
Pubblicato in:J Control Release
Autori principali: Jiang, Jinlin, Kao, Chen-Yuan, Papoutsakis, Eleftherios T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804484/
https://ncbi.nlm.nih.gov/pubmed/28024915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.12.021
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