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Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells
In vivo visualization of thrombopoiesis suggests an important role for shear flow in platelet biogenesis. In vitro, shear stress was shown to accelerate proplatelet formation from mature megakaryocytes (Mks). Yet, the role of biomechanical forces on Mk biology and platelet biogenesis remains largely...
Gorde:
| Egile Nagusiak: | , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society of Hematology
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186538/ https://ncbi.nlm.nih.gov/pubmed/24948658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-547927 |
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