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Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells
In vivo visualization of thrombopoiesis suggests an important role for shear flow in platelet biogenesis. In vitro, shear stress was shown to accelerate proplatelet formation from mature megakaryocytes (Mks). Yet, the role of biomechanical forces on Mk biology and platelet biogenesis remains largely...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186538/ https://ncbi.nlm.nih.gov/pubmed/24948658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-547927 |
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