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Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes

Blood platelets are essential for controlling hemostasis. They are released by megakaryocytes (MKs) located in the bone marrow, upon extension of cytoplasmic protrusions into the lumen of bone marrow sinusoids. Their number increases in postpulmonary capillaries, suggesting a role for oxygen gradien...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Poirault-Chassac, Sonia, Nivet-Antoine, Valérie, Houvert, Amandine, Kauskot, Alexandre, Lauret, Evelyne, Lai-Kuen, René, Dusanter-Fourt, Isabelle, Baruch, Dominique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993111/
https://ncbi.nlm.nih.gov/pubmed/33720340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002847
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