SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

Megakaryocyte (MK) development in the bone marrow progresses spatially from the endosteal niche, which promotes MK progenitor proliferation, to the sinusoidal vascular niche, the site of terminal maturation and thrombopoiesis. The chemokine stromal cell-derived factor-1 (SDF-1), signaling through CX...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Niswander, Lisa M., Fegan, Katherine H., Kingsley, Paul D., McGrath, Kathleen E., Palis, James
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2014
Pynciau:
Platelets and Thrombopoiesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093683/
https://ncbi.nlm.nih.gov/pubmed/24735964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-547638
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg