SDF-1 dynamically mediates megakaryocyte niche occupancy and thrombopoiesis at steady state and following radiation injury

Megakaryocyte (MK) development in the bone marrow progresses spatially from the endosteal niche, which promotes MK progenitor proliferation, to the sinusoidal vascular niche, the site of terminal maturation and thrombopoiesis. The chemokine stromal cell-derived factor-1 (SDF-1), signaling through CX...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Niswander, Lisa M., Fegan, Katherine H., Kingsley, Paul D., McGrath, Kathleen E., Palis, James
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2014
Gaiak:
Platelets and Thrombopoiesis
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4093683/
https://ncbi.nlm.nih.gov/pubmed/24735964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-547638
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