Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes

Blood platelets are essential for controlling hemostasis. They are released by megakaryocytes (MKs) located in the bone marrow, upon extension of cytoplasmic protrusions into the lumen of bone marrow sinusoids. Their number increases in postpulmonary capillaries, suggesting a role for oxygen gradien...

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Bibliografische gegevens
Gepubliceerd in:Blood Adv
Hoofdauteurs: Poirault-Chassac, Sonia, Nivet-Antoine, Valérie, Houvert, Amandine, Kauskot, Alexandre, Lauret, Evelyne, Lai-Kuen, René, Dusanter-Fourt, Isabelle, Baruch, Dominique
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2021
Onderwerpen:
Platelets and Thrombopoiesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993111/
https://ncbi.nlm.nih.gov/pubmed/33720340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002847
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