Role for MKL1 in megakaryocytic maturation

Megakaryoblastic leukemia 1 (MKL1), identified as part of the t(1;22) translocation specific to acute megakaryoblastic leukemia, is highly expressed in differentiated muscle cells and promotes muscle differentiation by activating serum response factor (SRF). Here we show that Mkl1 expression is up-r...

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Bibliografische gegevens
Hoofdauteurs: Cheng, Ee-chun, Luo, Qing, Bruscia, Emanuela M., Renda, Matthew J., Troy, James A., Massaro, Stephanie A., Tuck, David, Schulz, Vincent, Mane, Shrikant M., Berliner, Nancy, Sun, Yi, Morris, Stephan W., Qiu, Caihong, Krause, Diane S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2009
Onderwerpen:
Platelets and Thrombopoiesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661865/
https://ncbi.nlm.nih.gov/pubmed/19136660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-180596
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