Role for MKL1 in megakaryocytic maturation

Megakaryoblastic leukemia 1 (MKL1), identified as part of the t(1;22) translocation specific to acute megakaryoblastic leukemia, is highly expressed in differentiated muscle cells and promotes muscle differentiation by activating serum response factor (SRF). Here we show that Mkl1 expression is up-r...

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Detalles Bibliográficos
Autores principales: Cheng, Ee-chun, Luo, Qing, Bruscia, Emanuela M., Renda, Matthew J., Troy, James A., Massaro, Stephanie A., Tuck, David, Schulz, Vincent, Mane, Shrikant M., Berliner, Nancy, Sun, Yi, Morris, Stephan W., Qiu, Caihong, Krause, Diane S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Platelets and Thrombopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661865/
https://ncbi.nlm.nih.gov/pubmed/19136660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-180596
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