Role for MKL1 in megakaryocytic maturation

Megakaryoblastic leukemia 1 (MKL1), identified as part of the t(1;22) translocation specific to acute megakaryoblastic leukemia, is highly expressed in differentiated muscle cells and promotes muscle differentiation by activating serum response factor (SRF). Here we show that Mkl1 expression is up-r...

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Autors principals: Cheng, Ee-chun, Luo, Qing, Bruscia, Emanuela M., Renda, Matthew J., Troy, James A., Massaro, Stephanie A., Tuck, David, Schulz, Vincent, Mane, Shrikant M., Berliner, Nancy, Sun, Yi, Morris, Stephan W., Qiu, Caihong, Krause, Diane S.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2009
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661865/
https://ncbi.nlm.nih.gov/pubmed/19136660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-180596
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