Role for MKL1 in megakaryocytic maturation

Megakaryoblastic leukemia 1 (MKL1), identified as part of the t(1;22) translocation specific to acute megakaryoblastic leukemia, is highly expressed in differentiated muscle cells and promotes muscle differentiation by activating serum response factor (SRF). Here we show that Mkl1 expression is up-r...

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Detalhes bibliográficos
Principais autores: Cheng, Ee-chun, Luo, Qing, Bruscia, Emanuela M., Renda, Matthew J., Troy, James A., Massaro, Stephanie A., Tuck, David, Schulz, Vincent, Mane, Shrikant M., Berliner, Nancy, Sun, Yi, Morris, Stephan W., Qiu, Caihong, Krause, Diane S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661865/
https://ncbi.nlm.nih.gov/pubmed/19136660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-09-180596
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