Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes

Blood platelets are essential for controlling hemostasis. They are released by megakaryocytes (MKs) located in the bone marrow, upon extension of cytoplasmic protrusions into the lumen of bone marrow sinusoids. Their number increases in postpulmonary capillaries, suggesting a role for oxygen gradien...

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Dades bibliogràfiques
Publicat a:Blood Adv
Autors principals: Poirault-Chassac, Sonia, Nivet-Antoine, Valérie, Houvert, Amandine, Kauskot, Alexandre, Lauret, Evelyne, Lai-Kuen, René, Dusanter-Fourt, Isabelle, Baruch, Dominique
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2021
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993111/
https://ncbi.nlm.nih.gov/pubmed/33720340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002847
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