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Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes
Blood platelets are essential for controlling hemostasis. They are released by megakaryocytes (MKs) located in the bone marrow, upon extension of cytoplasmic protrusions into the lumen of bone marrow sinusoids. Their number increases in postpulmonary capillaries, suggesting a role for oxygen gradien...
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| Pubblicato in: | Blood Adv |
|---|---|
| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society of Hematology
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7993111/ https://ncbi.nlm.nih.gov/pubmed/33720340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002847 |
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