Mitochondrial dynamics and reactive oxygen species initiate thrombopoiesis from mature megakaryocytes

Blood platelets are essential for controlling hemostasis. They are released by megakaryocytes (MKs) located in the bone marrow, upon extension of cytoplasmic protrusions into the lumen of bone marrow sinusoids. Their number increases in postpulmonary capillaries, suggesting a role for oxygen gradien...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: Poirault-Chassac, Sonia, Nivet-Antoine, Valérie, Houvert, Amandine, Kauskot, Alexandre, Lauret, Evelyne, Lai-Kuen, René, Dusanter-Fourt, Isabelle, Baruch, Dominique
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2021
Pynciau:
Platelets and Thrombopoiesis
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7993111/
https://ncbi.nlm.nih.gov/pubmed/33720340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2020002847
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