Three-Dimensional Environment Sustains Hematopoietic Stem Cell Differentiation into Platelet-Producing Megakaryocytes

Hematopoietic stem cells (HSC) differentiate into megakaryocytes (MK), whose function is to release platelets. Attempts to improve in vitro platelet production have been hampered by the low amplification of MK. Providing HSC with an optimal three-dimensional (3D) architecture may favor MK differenti...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Pietrzyk-Nivau, Audrey, Poirault-Chassac, Sonia, Gandrille, Sophie, Derkaoui, Sidi-Mohammed, Kauskot, Alexandre, Letourneur, Didier, Le Visage, Catherine, Baruch, Dominique
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2015
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4552162/
https://ncbi.nlm.nih.gov/pubmed/26313154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136652
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