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Microfluidic model of the platelet-generating organ: beyond bone marrow biomimetics
We present a new, rapid method for producing blood platelets in vitro from cultured megakaryocytes based on a microfluidic device. This device consists in a wide array of VWF-coated micropillars. Such pillars act as anchors on megakaryocytes, allowing them to remain trapped in the device and subject...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4761988/ https://ncbi.nlm.nih.gov/pubmed/26898346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21700 |
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