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Shear enhances thrombopoiesis and formation of microparticles that induce megakaryocytic differentiation of stem cells

In vivo visualization of thrombopoiesis suggests an important role for shear flow in platelet biogenesis. In vitro, shear stress was shown to accelerate proplatelet formation from mature megakaryocytes (Mks). Yet, the role of biomechanical forces on Mk biology and platelet biogenesis remains largely...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jiang, Jinlin, Woulfe, Donna S., Papoutsakis, Eleftherios T.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186538/
https://ncbi.nlm.nih.gov/pubmed/24948658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-547927
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