Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation

Platelets are essential in maintaining hemostasis following inflammation or injury to the vasculature. Dysregulated platelet activity often results in thrombotic complications leading to myocardial infarction and stroke. Activation of the FcγRIIa receptor leads to immune-mediated thrombosis, which i...

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Bibliografische gegevens
Hoofdauteurs: Yeung, Jennifer, Tourdot, Benjamin E., Fernandez-Perez, Pilar, Vesci, Joanne, Ren, Jin, Smyrniotis, Christopher J., Luci, Diane K., Jadhav, Ajit, Simeonov, Anton, Maloney, David J., Holman, Theodore R., McKenzie, Steven E., Holinstat, Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2014
Onderwerpen:
Platelets and Thrombopoiesis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183986/
https://ncbi.nlm.nih.gov/pubmed/25100742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-575878
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