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Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4

Bacterial adhesion to platelets is mediated via a range of strain-specific bacterial surface proteins that bind to a variety of platelet receptors. It is unclear how these interactions lead to platelet activation. We demonstrate a critical role for the immune receptor FcγRIIA, αIIbβ3, and Src and Sy...

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Autors principals: Arman, Mònica, Krauel, Krystin, Tilley, Dorothea O., Weber, Claudia, Cox, Dermot, Greinacher, Andreas, Kerrigan, Steven W., Watson, Steve P.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023422/
https://ncbi.nlm.nih.gov/pubmed/24642751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-540526
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