Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation

Platelets are essential in maintaining hemostasis following inflammation or injury to the vasculature. Dysregulated platelet activity often results in thrombotic complications leading to myocardial infarction and stroke. Activation of the FcγRIIa receptor leads to immune-mediated thrombosis, which i...

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Autors principals: Yeung, Jennifer, Tourdot, Benjamin E., Fernandez-Perez, Pilar, Vesci, Joanne, Ren, Jin, Smyrniotis, Christopher J., Luci, Diane K., Jadhav, Ajit, Simeonov, Anton, Maloney, David J., Holman, Theodore R., McKenzie, Steven E., Holinstat, Michael
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2014
Matèries:
Platelets and Thrombopoiesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183986/
https://ncbi.nlm.nih.gov/pubmed/25100742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-575878
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