Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation

Platelets are essential in maintaining hemostasis following inflammation or injury to the vasculature. Dysregulated platelet activity often results in thrombotic complications leading to myocardial infarction and stroke. Activation of the FcγRIIa receptor leads to immune-mediated thrombosis, which i...

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Detalhes bibliográficos
Main Authors: Yeung, Jennifer, Tourdot, Benjamin E., Fernandez-Perez, Pilar, Vesci, Joanne, Ren, Jin, Smyrniotis, Christopher J., Luci, Diane K., Jadhav, Ajit, Simeonov, Anton, Maloney, David J., Holman, Theodore R., McKenzie, Steven E., Holinstat, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183986/
https://ncbi.nlm.nih.gov/pubmed/25100742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-05-575878
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