FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease characterized by deposits of immune complexes (ICs) in organs and tissues. The expression of FcγRIIA by human platelets, which is their unique receptor for immunoglobulin G antibodies, positions them to ideally respond to circu...

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Опубликовано в: :Blood
Главные авторы: Melki, Imene, Allaeys, Isabelle, Tessandier, Nicolas, Mailhot, Benoit, Cloutier, Nathalie, Campbell, Robert A., Rowley, Jesse W., Salem, David, Zufferey, Anne, Laroche, Audrée, Lévesque, Tania, Patey, Natalie, Rauch, Joyce, Lood, Christian, Droit, Arnaud, McKenzie, Steven E., Machlus, Kellie R., Rondina, Matthew T., Lacroix, Steve, Fortin, Paul R., Boilard, Eric
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2020
Предметы:
Platelets and Thrombopoiesis
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7751357/
https://ncbi.nlm.nih.gov/pubmed/33331924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020004974
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