Structural basis for quinine-dependent antibody binding to platelet integrin α(IIb)β(3)

Drug-induced immune thrombocytopenia (DITP) is caused by antibodies that react with specific platelet-membrane glycoproteins when the provoking drug is present. More than 100 drugs have been implicated as triggers for this condition, quinine being one of the most common. The cause of DITP in most ca...

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Bibliografiske detaljer
Udgivet i:Blood
Main Authors: Zhu, Jianghai, Zhu, Jieqing, Bougie, Daniel W., Aster, Richard H., Springer, Timothy A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2015
Fag:
Platelets and Thrombopoiesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4626254/
https://ncbi.nlm.nih.gov/pubmed/26282540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-639351
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