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Mechanism of quinine-dependent monoclonal antibody binding to platelet glycoprotein IIb/IIIa
Drug-dependent antibodies (DDAbs) that cause acute thrombocytopenia upon drug exposure are nonreactive in the absence of the drug but bind tightly to a platelet membrane glycoprotein, usually α(IIb)/β(3) integrin (GPIIb/IIIa) when the drug is present. How a drug promotes binding of antibody to its t...
Tallennettuna:
| Julkaisussa: | Blood |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Society of Hematology
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4626255/ https://ncbi.nlm.nih.gov/pubmed/26353910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-04-643148 |
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