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Tubulin polymerization disrupts cardiac β-adrenergic regulation of late I(Na)
AIMS: The anticancer drug paclitaxel (TXL) that polymerizes microtubules is associated with arrhythmias and sinus node dysfunction. TXL can alter membrane expression of Na channels (Na(V)1.5) and Na current (I(Na)), but the mechanisms are unknown. Calcium/calmodulin-dependent protein kinase II (CaMK...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133594/ https://ncbi.nlm.nih.gov/pubmed/24812278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvu120 |
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