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Nanoimages show disruption of tubulin polymerization by chlorpyrifos oxon; implications for neurotoxicity

Organophosphorus agents cause cognitive deficits and depression in some people. We hypothesize that the mechanism by which organophosphorus agents cause these disorders is by modification of proteins in the brain. One such protein could be tubulin. Tubulin polymerizes to make the microtubules that t...

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Bibliografski detalji
Glavni autori: Grigoryan, Hasmik, Lockridge, Oksana
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753691/
https://ncbi.nlm.nih.gov/pubmed/19631231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.07.015
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