ロード中...

Mass spectrometry identifies covalent binding of soman, sarin, chlorpyrifos oxon, diisopropyl fluorophosphate, and FP-biotin to tyrosines on tubulin: a potential mechanism of long term toxicity by organophosphorus agents

Chronic low dose exposure to organophosphorus poisons (OP) results in cognitive impairment. Studies in rats have shown that OP interfere with microtubule polymerization. Since microtubules are required for transport of nutrients from the nerve cell body to the nerve synapse, it has been suggested th...

詳細記述

保存先:
書誌詳細
主要な著者: Grigoryan, Hasmik, Schopfer, Lawrence M., Thompson, Charles M., Terry, Alvin V., Masson, Patrick, Lockridge, Oksana
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577157/
https://ncbi.nlm.nih.gov/pubmed/18502412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2008.04.013
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!