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Covalent binding of the organophosphorus agent FP-biotin to tyrosine in eight proteins that have no active site serine
Organophosphorus esters (OP) are known to bind covalently to the active site serine of enzymes in the serine hydrolase family. It was a surprise to find that proteins with no active site serine are also covalently modified by OP. The binding site in albumin, transferrin, and tubulin was identified a...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700782/ https://ncbi.nlm.nih.gov/pubmed/19539807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2009.03.018 |
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