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Cresyl Saligenin Phosphate, an Organophosphorus Toxicant, Makes Covalent Adducts with Histidine, Lysine and Tyrosine Residues of Human Serum Albumin

CBDP (2-(2-cresyl)-4H-1-3-2-benzodioxaphosphorin-2-oxide) is a toxic organophosphorus compound. It is generated in vivo from tri-ortho-cresyl phosphate (TOCP), a component of jet engine oil and hydraulic fluids. Exposure to TOCP was proven to occur on board aircraft by finding CBDP-derived phospho-b...

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Autors principals: Liyasova, Mariya S., Schopfer, Lawrence M., Lockridge, Oksana
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427739/
https://ncbi.nlm.nih.gov/pubmed/22793878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300215g
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