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Chlorpyrifos Oxon-Induced Isopeptide Bond Formation in Human Butyrylcholinesterase
A newly recognized action of organophosphates (OP) is the ability to crosslink proteins through an isopeptide bond. The first step in the mechanism is covalent addition of the OP to the side chain of lysine. This activates OP-lysine for reaction with a nearby glutamic or aspartic acid to make a gamm...
Gardado en:
| Publicado en: | Molecules |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7037448/ https://ncbi.nlm.nih.gov/pubmed/31991818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25030533 |
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