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Taxol binds to polymerized tubulin in vitro

Taxol, a natural plant product that enhances the rate and extent of microtubule assembly in vitro and stabilizes microtubules in vitro and in cells, was labeled with tritium by catalytic exchange with (3)H(2)O. The binding of [(3)H]taxol to microtubule protein was studied by a sedimentation assay. M...

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Detalhes bibliográficos
Main Authors: Parness, J, Horwitz, SB
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111958/
https://ncbi.nlm.nih.gov/pubmed/6118377
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