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Taxol binds to polymerized tubulin in vitro

Taxol, a natural plant product that enhances the rate and extent of microtubule assembly in vitro and stabilizes microtubules in vitro and in cells, was labeled with tritium by catalytic exchange with (3)H(2)O. The binding of [(3)H]taxol to microtubule protein was studied by a sedimentation assay. M...

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Main Authors: Parness, J, Horwitz, SB
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 1981
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2111958/
https://ncbi.nlm.nih.gov/pubmed/6118377
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