Comparison of Epothilone and Taxol Binding in Yeast Tubulin using Molecular Modeling

Microtubules are unique cytoskeletal structures that have structural subunits of αβ tubulin. Taxol is a typical microtubule stabilizing drug. The epothilones are other natural products with similar mechanism of action totaxol. Despite the highly conserved nature of β-tubulin, some organism like Sacc...

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Bibliografiska uppgifter
Huvudupphovsmän: Akbari, Vajihe, Moghim, Sharareh, Reza Mofid, Mohammad
Materialtyp: Artigo
Språk:Inglês
Publicerad: Avicenna Research Institute 2011
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3558196/
https://ncbi.nlm.nih.gov/pubmed/23407671
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