The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density
The chemotherapeutic drug Taxol is known to interact within a specific site on β-tubulin. Although the general location of the site has been defined by photoaffinity labeling and electron crystallography, the original data were insufficient to make an absolute determination of the bound conformation...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33206/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11309480/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.051309398 |
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