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The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density
The chemotherapeutic drug Taxol is known to interact within a specific site on β-tubulin. Although the general location of the site has been defined by photoaffinity labeling and electron crystallography, the original data were insufficient to make an absolute determination of the bound conformation...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33206/ https://ncbi.nlm.nih.gov/pubmed/11309480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051309398 |
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