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The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density

The chemotherapeutic drug Taxol is known to interact within a specific site on β-tubulin. Although the general location of the site has been defined by photoaffinity labeling and electron crystallography, the original data were insufficient to make an absolute determination of the bound conformation...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Snyder, James P., Nettles, James H., Cornett, Ben, Downing, Kenneth H., Nogales, Eva
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The National Academy of Sciences 2001
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC33206/
https://ncbi.nlm.nih.gov/pubmed/11309480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051309398
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