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The binding conformation of Taxol in β-tubulin: A model based on electron crystallographic density

The chemotherapeutic drug Taxol is known to interact within a specific site on β-tubulin. Although the general location of the site has been defined by photoaffinity labeling and electron crystallography, the original data were insufficient to make an absolute determination of the bound conformation...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Snyder, James P., Nettles, James H., Cornett, Ben, Downing, Kenneth H., Nogales, Eva
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2001
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC33206/
https://ncbi.nlm.nih.gov/pubmed/11309480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051309398
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