Plinabulin, an inhibitor of tubulin polymerization, targets KRAS signaling through disruption of endosomal recycling

Constitutive activation of Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most common oncogenic event in certain types of human cancer and is associated with poor patient survival. Small molecule signaling inhibitors have improved the clinical outcomes of patients with various cancer types...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Biomed Rep
Autori principali: Cimino, Patrick J., Huang, Lan, Du, Lihua, Wu, Yanping, Bishop, Jamie, Dalsing-Hernandez, Jessica, Kotlarczyk, Kari, Gonzales, Paul, Carew, Jennifer, Nawrocki, Steffan, Jordan, Mary Ann, Wilson, Leslie, Lloyd, G. Kenneth, Wirsching, Hans-Georg
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439430/
https://ncbi.nlm.nih.gov/pubmed/30972217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2019.1196
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi