Plinabulin, an inhibitor of tubulin polymerization, targets KRAS signaling through disruption of endosomal recycling

Constitutive activation of Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most common oncogenic event in certain types of human cancer and is associated with poor patient survival. Small molecule signaling inhibitors have improved the clinical outcomes of patients with various cancer types...

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Detalhes bibliográficos
Publicado no:Biomed Rep
Main Authors: Cimino, Patrick J., Huang, Lan, Du, Lihua, Wu, Yanping, Bishop, Jamie, Dalsing-Hernandez, Jessica, Kotlarczyk, Kari, Gonzales, Paul, Carew, Jennifer, Nawrocki, Steffan, Jordan, Mary Ann, Wilson, Leslie, Lloyd, G. Kenneth, Wirsching, Hans-Georg
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6439430/
https://ncbi.nlm.nih.gov/pubmed/30972217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2019.1196
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