Načítá se...

Catalytic and non-catalytic roles of the CtIP endonuclease in double-strand break end resection

The CtIP protein is known to function in 5′ strand resection during homologous recombination similar to the budding yeast Sae2 protein, although its role in this process is unclear. Here we characterize recombinant human CtIP and find that it exhibits 5′ flap endonuclease activity on branched DNA st...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Makharashvili, Nodar, Tubbs, Anthony T., Yang, Soo-Hyun, Wang, Hailong, Barton, Olivia, Zhou, Yi, Deshpande, Rajashree A., Lee, Ji-Hoon, Lobrich, Markus, Sleckman, Barry P., Wu, Xiaohua, Paull, Tanya T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079050/
https://ncbi.nlm.nih.gov/pubmed/24837676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.04.011
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!