Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1

DNA double-strand breaks (DSBs) are repaired by nonhomologous end joining (NHEJ) or homologous recombination (HR). The C terminal binding protein–interacting protein (CtIP) is phosphorylated in G2 by cyclin-dependent kinases to initiate resection and promote HR. CtIP also exerts functions during NHE...

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Bibliographic Details
Main Authors: Barton, Olivia, Naumann, Steffen C., Diemer-Biehs, Ronja, Künzel, Julia, Steinlage, Monika, Conrad, Sandro, Makharashvili, Nodar, Wang, Jiadong, Feng, Lin, Lopez, Bernard S., Paull, Tanya T., Chen, Junjie, Jeggo, Penny A., Löbrich, Markus
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178966/
https://ncbi.nlm.nih.gov/pubmed/25267294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201401146
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