Structural rearrangements of a polyketide synthase module during its catalytic cycle

The polyketide synthase (PKS) mega-enzyme assembly line uses a modular architecture to synthesize diverse and bioactive natural products that often constitute the core structures or complete chemical entities for many clinically approved therapeutic agents(1). The architecture of a full-length PKS m...

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Detaylı Bibliyografya
Asıl Yazarlar: Whicher, Jonathan R., Dutta, Somnath, Hansen, Douglas A., Hale, Wendi A., Chemler, Joseph A., Dosey, Annie M., Narayan, Alison R., Håkansson, Kristina, Sherman, David H., Smith, Janet L., Skiniotis, Georgios
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074775/
https://ncbi.nlm.nih.gov/pubmed/24965656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13409
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