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Architecture of the polyketide synthase module: surprises from electron cryo-microscopy
Modular polyketide synthases produce a vast array of bioactive molecules that are the basis of many highly valued pharmaceuticals. The biosynthesis of these compounds is based on ordered assembly lines of multi-domain modules, each extending and modifying a specific chain-elongation intermediate bef...
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| Опубликовано в: : | Curr Opin Struct Biol |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4476912/ https://ncbi.nlm.nih.gov/pubmed/25791608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2015.02.014 |
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