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Structural rearrangements of a polyketide synthase module during its catalytic cycle
The polyketide synthase (PKS) mega-enzyme assembly line uses a modular architecture to synthesize diverse and bioactive natural products that often constitute the core structures or complete chemical entities for many clinically approved therapeutic agents(1). The architecture of a full-length PKS m...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4074775/ https://ncbi.nlm.nih.gov/pubmed/24965656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13409 |
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