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Substrate Controlled Divergence in Polyketide Synthase Catalysis
[Image: see text] Biochemical characterization of polyketide synthases (PKSs) has relied on synthetic substrates functionalized as electrophilic esters to acylate the enzyme and initiate the catalytic cycle. In these efforts, N-acetylcysteamine thioesters have typically been employed for in vitro st...
Shranjeno v:
| izdano v: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2015
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4379966/ https://ncbi.nlm.nih.gov/pubmed/25730816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja511743n |
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