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The structural organization of substrate loading in iterative polyketide synthases
Polyketide synthases (PKSs) are microbial multienzymes for the biosynthesis of biologically potent secondary metabolites. Polyketide production is initiated by the loading of a starter unit onto an integral acyl carrier protein (ACP) and its subsequent transfer to the ketosynthase (KS). Initial subs...
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| 發表在: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6196715/ https://ncbi.nlm.nih.gov/pubmed/29610486 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-018-0026-3 |
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