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Deconstruction of Iterative Multidomain Polyketide Synthase Function
PksA, which initiates biosynthesis of the environmental carcinogen aflatoxin B1, is one of the multidomain iterative polyketide synthases (IPKSs), a large, poorly understood family of biosynthetic enzymes. We found that dissection of PksA and its reconstitution from selected sets of domains allows t...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2480491/ https://ncbi.nlm.nih.gov/pubmed/18403714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1154711 |
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